Conjugation: HRP: Horseradish Peroxidase
Description of Target: PCSK6 is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. This gene is thought to play a role in tumor progression.The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified.
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PCSK6
Key Reference: Yuasa,K., Gene 402 (1-2), 103-110 (2007)
Molecular Weight: 91kDa
Peptide Sequence: Synthetic peptide located within the following region:
NYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIProduct Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Protein Name: Proprotein convertase subtilisin/kexin type 6
Protein Size: 975
Purification: Affinity Purified
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