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Applications: Useful for the study of protein-protein interaction and in vitro and in vivo protein function studies.
Description: Mouse secreted Programmed Cell Death 1 (PD-1)-Fc fusion protein, also known as CD279, PDCD1, and SLEB2, GenBank Accession No. NM_008798, a.a. 25-167, fused at the C-terminus to the Fc portion of mouse IgG2a and with a C-terminal Avi-tag, expressed in a HEK293 cell expression system. This protein was biotinylated using Avi-Tag™ technology. MW = 45 kDa. Note: this protein runs at an apparent higher molecular weight due to glycosylation.
Formulation: 8 mM Na Phosphate pH 7.4, 110 mM NaCl, 2.2 mM KCl and 20% glycerol.
Genbank: NM_008798
Storage Stability: At least 6 months at -80°C.
Supplied As: Aqueous buffer solution.
Tags: C-terminal Fc fusion (Mouse IgG2a), C-terminal Avi-tag™
Uniprot: Q02242
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Agata, Y., et al., Internat. Immunol. 1996; 8(5): 765-772.2. Freeman, G.J. et al., J. Exp. Med. 2000; 192(7): 1027-1034.
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