Formulation: A solid
Formal Name: 3-[2-[4-(3,4-dimethylphenyl)-1-piperazinyl]ethyl]-2,3-dihydro-1H-isoindol-1-one, dihydrochloride
Purity: ≥98%
Formula Markup: C22H27N3O • 2HCl
Formula Weight: 422,4
Shelf life (days): 1460
CAS Number: 1782532-06-2
Notes: PD 168568 is a dopamine D4 receptor antagonist (Ki = 8.8 nM).{65147} It is selective for dopamine D4 over D2 receptors (Ki = 1,842 nM). PD 168568 (3 mg/kg) reverses amphetamine-induced hyperlocomotion in rats. It also inhibits the growth of glioblastoma neural stem cells when used at concentrations of 25 and 50 µM.{65146}