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Applications: Useful for the study of protein-protein interaction and in vitro and in vivo protein function studies.
Description: Mouse secreted Programmed Cell Death 1Ligand 1 (PD-L1)-Fc fusion protein, alsoknown as CD274 and B7 homolog 1 (B7-H1), GenBank Accession No. NM_021893,a.a. 19-238, fused at the C-terminus to theFc portion of mouse IgG2a, expressed in aHEK293 cell expression system. MW = 51.8kDa.
Format: Aqueous buffer solution
Formulation: 8 mM Na Phosphate pH 7.4, 110 mM NaCl, 2.2 mM KCl and 20% glycerol.
Genbank: NM_021893
Storage Stability: At least 6 months at -80°C.
Tags: C-terminal Fc fusion (Mouse IgG2a)
Uniprot: Q9EP73
Warnings: Avoidfreeze/thaw cycles. Storing diluted protein isnot recommended, if necessary, use carrierprotein (BSA 0.1 - 0.5%).
Biosafety Level: Not applicable (BSL-1)
References: 1. Freeman, G.J., et al., J. Exp. Med. 2000; 192(7):1027-34.
2. Dong, H., et al., Nat. Med. 1999; 5(12):1365-9.Product Specific Reference(s):
1. Lmai, Y., et al., J. Immunol. 2015; 195(2): 421-425.