PD-L1 / PDCD1LG1 / CD274 / B7-H1 (Cancer Immunotherapy Target)(PDL1/2745), 1mg/mL

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Description: PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: PDL1/2745

Entrez Gene ID: 29126

Immunogen: Recombinant fragment of human CD274 protein (around aa 39-191) (exact sequence is proprietary)

• SKU: BTMBNUM2745-50
• Manufacturer: Biotium
• Manufacturer SKU: BNUM2745-50
• Package Unit: 50 uL
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1 kappa
• Host: Mouse
• Conjugate: Unconjugated