Clone Name: RMP1-30
Light Chain: Kappa
Product Description: The RMP1-30 antibody is specific for mouse CD279, also known as programmed death-1 (PD-1), a 55 kDa glycoprotein member of the Ig superfamily of molecules. PD-1 exists in a monomeric form that is expressed by CD4- CD8- thymocytes, where it participates in the processes of clonal selection, elimination of autoreactive lymphocytes, and development of tolerance. PD-1 expression is also inducible upon activation of mature T cells, where it has been proposed to interact with the co-stimulatory receptor CD80 to limit T cell activation. Two ligands for PD-1, known as PD-L1 (B7-H1) and PD-L2 (B7-DC) are differentially expressed on T and B cells, monocytes, macrophages, NK cells or dendritic cells.
Calculated MW: 32
Form: Liquid
Buffer (with preservative): 10mM NaH₂PO₄, 150mM NaCl, 0.09% Sodium azide.
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Uniprot ID: Q02242
Antigen Species: Mouse
Immunogen: PD-1 transferred BHK cells.
Purification: Purified by affinity chromatography
Conjugation: Unconjugated
Full Name: programmed cell death 1
English
Deutsch
