PD325901, CAS 391210-10-9

MEK kinase inhibitor

Product Type: Inhibitor

CAS No.: 391210-10-9

MolecularFormula: C16H14F3IN2O4

Molecular Weight: 482,2

Source: Synthetic

Purity: ≥98% (HPLC)

Solubility: Soluble to 25 mM in DMSO

Appearance: Off-white solid

PubChem CID: 9826528

Scientific Background: PD325901 is a potent MEK1 and MEK2 inhibitor. Specifically, it has been shown to suppress phosphorylation of ERK1/2 in murine colon 26 cells, as well as, its downstream target, ribosomal S6 kinase, in a dose-dependent manner.

References: 1. Barrett S.D., et al. (2008) Bioorganic. Med. Chem. Letters. 18(24): 6501–6504.2. Ciuffreda L., et al. (2009) Neoplasia. 11(8): 720–731.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-507-5MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-507-5MG
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK