PE/Elab Fluor 594 Anti-Mouse CD86 Antibody(GL-1), Rat, Monoclonal

Swissprot: P42082.

Background: CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Abbre: Mouse CD86.

Buffer: PBS with 0.05% Proclin300, 1% BSA.

Clone No: GL-1.

Conjugation: PE/Elab Fluor® 594.

• SKU: ELSE-AB-F0994P-50
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-E-AB-F0994P-50
• Package Unit: 50 Tests
• Quantity Unit: PAK
• Reactivity: Mouse (Murine)
• Clonality: Monoclonal
• Application: Flow Cytometry
• Human Gene ID: 12524
• Host: Rat