Formulation: A solid
Formal Name: (R)-2,3-bis(stearoyloxy)propyl (138-oxo-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80,83,86,89,92,95,98,101,104,107,110,113,116,119,122,125,128,131,134,137-hexatetracontaoxa-139-azahentetracontahectan-141-yl) phosphate, monosodium salt
Purity: ≥95%
Formula Markup: C133H263NO55P • Na
Formula Weight: 2810,4
Shelf life (days): 730
Notes: PEG(2000)-DSPE is a PEGylated form of 1,2-distearoyl-sn-glycero-3-PE (DSPE; Item No. 15095).{68196} It has been used in the generation of micelles and in combination with other lipids in the formation of liposomes. Liposomes containing PEG(2000)-DSPE and encapsulating the DNA topoisomerase inhibitor doxorubicin (Item No. 15007) and the flavonoid quercetin (Item No. 10005169) reduce tumor growth in an MCF-7/adr multidrug-resistant breast cancer mouse xenograft model.
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