Mouse anti Pepsinogen I, clone 4C6.1 (Monoclonal)

Clone Number: 4C6.1

Immunogen: Pepsinogen I purified from human tissue

Concentration: 100 ug/ ml

Storage buffer: PBS with 1% BSA & 0.09% sodium azide

Additional info: The antibody is specific to human pepsinogen I and has no crossreactivity to human pepsinogen II. Pepsinogen I is a group of precursor molecules for pepsin. These proteins are solely synthetized and secreted into gastric lumen by chief (pepsin) cells and mucous neck cells in the gastric corpus (oxyntic mucosa). In atrophic corpus gastritis these cells disappear resulting in a decrease of the serum level of pepsinogen I and in a reduction of the number of pepsinogen I positive cells in gastric biopsies. The presence of positive immunostaining for pepsinogen I is a highly reliable sign for the acid-secreting oxyntic glands. In gastric heterotopia of the duodenal bulb, but not in gastric metaplasia, the oxyntic-type glands give a positive immunohistochemical reaction for pepsinogen I.

• SKU: SANMON7088
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: MON7088
• Package Unit: 1 ml
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunohistochemistry (frozen), Immunohistochemistry (paraffin), Western Blotting, ELISA
• Isotype: IgG1
• Host: Mouse
• Conjugate: Unconjugated