Formulation: A solid
Purity: ≥98%
Shelf life (days): 1460
CAS Number: 383907-64-0
Notes: Phosphatidylglycerol is a naturally occurring anionic phospholipid and a constituent of plant, animal, and bacterial cell membranes.{48042,48043} It is less abundant than phosphatidylethanolamine (Item Nos. 16878 / 24332) in prokaryotes and eukaryotes and phosphatidylcholine (Item Nos. 24343 / 24370) in eukaryotes. It is formed via a reaction between CDP-diglyceride with L-α-glycerol 3-phosphate followed by dephosphorylation and is a metabolic precursor of cardiolipin.{48042} Phosphatidylglycerol species containing polyunsaturated and monounsaturated fatty acyl chains inhibit and promote proliferation of murine keratinocytes, respectively.{48044} Phosphatidylglycerol is the second largest lipid component of mammalian lung surfactant, comprising 10% of the lipids, and levels are decreased in the lung surfactant of infants with respiratory distress syndrome.{48043} This product contains phosphatidylglycerol molecular species with variable fatty acyl chain lengths at the sn-1 and sn-2 positions.
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