Phospholamban (phospho Ser16) antibody (HL1710)

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Clone Name: HL1710

Light Chain: Kappa

Calculated MW: 6

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure, and also familial hypertrophic cardiomyopathy. [provided by RefSeq, Apr 2016]

Uniprot ID: P26678

Antigen Species: Human

Immunogen: Carrier-protein conjugated synthetic peptide surrounding phospho Ser16 of human phospholamban . The exact sequence is proprietary

Purification: Affinity purified by Protein A.

Conjugation: Unconjugated

Full Name: phospholamban

• SKU: GTX637309-100
• Manufacturer: GeneTex
• Manufacturer SKU: GTX637309-100
• Package Unit: 100 μl
• Quantity Unit: STK
• Reactivity: Mouse (Murine)
• Clonality: Recombinant
• Application: Western Blotting
• Isotype: IgG
• Human Gene ID: 5350
• Host: Rabbit
• Conjugate: Unconjugated