Product Type: Activator
CAS No.: 554-62-1
MolecularFormula: C18H39NO3
Molecular Weight: 317.5
Source: Isolated from Saccharomyces cerevisiae
Purity: >98% (TLC); NMR (Conforms)
Solubility: Soluble to 2 mg/ml in ethanol
Appearance: White powder
PubChem CID: 122121
Scientific Background: Phytosphingosine is a naturally occurring component found in yeast, plants and animals. In yeast, it is involved in mediating the heat stress response. Phytosphingosine has been found to be pro-apoptotic in certain cancer cell lines. It is thought to activate the p38 MAPK pathway, followed by release of cytochrome c and activation of caspase 3, ultimately leading to programed cell death.
References: 1. Fischer C., et al. (2013) Skin Pharmacol Physiol. 26(1): 36-44.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.