Zerencotrep, CAS 1628287-16-0

Product Description: Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels, inhibits (?)-englerin A-activated TRPC4/TRPC5 channels, with IC50s of 0.349 and 1.3 nM in cells, and shows no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, TRPM8[1].

Applications: Cancer-programmed cell death

Formula: C23H20ClF3N4O5

References: [1]Rubaiy HN, et al. Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels. J Biol Chem. 2017 May 19;292(20):8158-8173.

CAS Number: 1628287-16-0

Molecular Weight: 524.88

Compound Purity: 99.40

Research Area: Cancer

Solubility: DMSO : ≥ 100 mg/mL

Target: TRP Channel

• SKU: MEXHY-101507-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-101507-50
• Package Unit: 50 mg
• Quantity Unit: STK