Pifithrin mu , CAS 64984-31-2

Hsp70 inhibitor

Product Type: Inhibitor

CAS No.: 64984-31-2

MolecularFormula: C8H7NO2S

Molecular Weight: 181,2

Source: Synthetic

Purity: >98%

Solubility: Soluble in ethanol (110 mM) and in DMSO (110 mM)

Appearance: White to off-white solid

PubChem CID: 327653

Scientific Background: Selectively interacts with HSP70 and disrupts its association with co-chaperones and substrate proteins. It induces apoptosis and is cell permeable. Also, inhibits p53 binding to mitochondria by reducing its affinity for antiapoptotic proteins Bcl-2 and Bcl-XL. Looking for more information on HSP70? Visit our new HSP70 Scientific Resource Guide at http://www.HSP70.com.

References: 1. Leu J.L., et al. (2009) Mol. Cell. 36: 15.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-325-50MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-325-50MG
• Package Unit: 50 mg
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine)