Product Type: Inducer
CAS No.: 20069-09-4
MolecularFormula: C17H19NO5
Molecular Weight: 317,3
Source: Synthetic
Purity: >98%
Solubility: Soluble in 25 mg/ml DMSO
Appearance: Cream Solid
PubChem CID: 637858
Scientific Background: Piperlongumine is a novel compound that exhibits a potential inhibitory effect on washed rabbit platelet aggregation induced by collagen, arachidonic acid and platelet activating factor, without any inhibiting effect on that induced by thrombin (1). It has recently been found to kill cancer cells by blocking the response that dissipates high oxidative stress and the resulting reactive oxygen species (ROS) generated, meanwhile sparing normal cells (2).
References: 1. Park B.S., et al. (2008) Phytother Res. 22(9): 1195-1199.2. Raj L., et al. (2011) Nature. 475(7355): 231.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
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