PK-11195, CAS 85532-75-8

Mitochondrial Benzodiazepine receptor ligand

Product Type: Inducer

CAS No.: 85532-75-8

MolecularFormula: C21H21CIN2O

Molecular Weight: 352,86

Source: Synthetic

Purity: >98%

Solubility: Soluble to 75 mM in ethanol and to 100 mM in DMSO

Appearance: White Crystals

PubChem CID: 1345

Scientific Background: PK-11195 is an isoquinoline carboxamide which binds selectively to the peripheral benzodiazepine receptor (PBR). It has a high affinity for the PBR in all species (1). It has also been successfully used in PET scans to visualize brain inflammation in patients with neuronal damage (2).

References: 1. Pike V.W., et al. (1993) Nucl Med & Bio. 20(4): 503-525.2. Buck J.R., et al. (2011) J Nucl Med. 52(1): 107-114.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-224-5MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-224-5MG
• Package Unit: 5 mg
• Quantity Unit: STK