Abbreviation: PLAA
Target Synonym: PLAA;DOA1;PLA2P;PLAP;NDMSBA
Conjugation: Unconjugated
UNIProt ID: Q9Y263
Background: Plays a role in protein ubiquitination, sorting and degradation through its association with VCP. Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling (By similarity. May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes. Plays a role in cerebellar Purkinje cell development (By similarity. Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha (TNF-alpha- or lipopolysaccharide (LPS-dependent manner, and hence prostaglandin E2 biosynthesis.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human PLAA
Dilution: WB 1:200-1:2000
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