Clone Name: 8A9
Light Chain: Kappa
Application Note: IHC-P: 1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 58
Specificity/Sensitivity: Immunohistochemical evidence (in house and published) supports reactivity with PLAP and also with PLAP-like enzyme.
Form: Liquid
Buffer (with preservative): Tissue culture supernatant, 0.09% Sodium azide.
Concentration:
Background: The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells. [provided by RefSeq, Jan 2015]
Uniprot ID: P05187
Antigen Species: Human
Immunogen: Purified human placental alkaline phosphatase.
Purification: Unpurified
Conjugation: Unconjugated
Full Name: alkaline phosphatase, placental
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