Application Note: WB: 1:500-1:2000. ICC/IF: 1:100-1:500. IHC-P: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 68
Form: Liquid
Buffer (with preservative): PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy. [provided by RefSeq, Sep 2015]
Uniprot ID: P53350
Antigen Species: Human
Immunogen: A synthesized peptide derived from Human PLK1 (Accession P53350), corresponding to amino acid residues D194-V222.
Purification: Purified by sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns
Conjugation: Unconjugated
Full Name: polo like kinase 1
English
Deutsch
