Product Type: Activator
CAS No.: 16561-29-8
MolecularFormula: C36H58O8
Molecular Weight: 616,8
Source: Synthetic
Purity: ≥99% (TLC)
Solubility: Soluble in DMSO (25 mg/ml), 100% ethanol (25 mg/ml), acetone, ether or dimethyl formamide; almost insoluble in aqueous buffers
Appearance: Colorless amorphous film or foam
PubChem CID: 27924
Scientific Background: PMA (Phorbol 12-myristate 13-acetate) is a phorbol ester. It is used experimentally as a reversible protein kinase C (PKC) activator. It has been shown to be a potent tumor promoter.
References: 1. Murphy T. V., Prountzos C., Kotsonis P., Iannazzo L., & Majewski H. (1999). Euro.J. Pharm. 381(1): 77–84.2. Castagna M., et al. (1982) J. Biol. Chem. 257(13): 7847–7851.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.