PMA, CAS 16561-29-8

PKC kinase activator

Product Type: Activator

CAS No.: 16561-29-8

MolecularFormula: C36H58O8

Molecular Weight: 616,8

Source: Synthetic

Purity: ≥99% (TLC)

Solubility: Soluble in DMSO (25 mg/ml), 100% ethanol (25 mg/ml), acetone, ether or dimethyl formamide; almost insoluble in aqueous buffers

Appearance: Colorless amorphous film or foam

PubChem CID: 27924

Scientific Background: PMA (Phorbol 12-myristate 13-acetate) is a phorbol ester. It is used experimentally as a reversible protein kinase C (PKC) activator. It has been shown to be a potent tumor promoter.

References: 1. Murphy T. V., Prountzos C., Kotsonis P., Iannazzo L., & Majewski H. (1999). Euro.J. Pharm. 381(1): 77–84.2. Castagna M., et al. (1982) J. Biol. Chem. 257(13): 7847–7851.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-508-5MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-508-5MG
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK