PMEL Polyclonal Antibody, Rabbit

Abbreviation: PMEL

Target Synonym: PMEL;D12S53E;ME20;ME20-M;ME20M;P1;P100;PMEL17;SI;SIL;SILV;gp100

Conjugation: Unconjugated

UNIProt ID: P40967

Background: This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human PMEL

Dilution: WB 1:500-1:2000,IF 1:50-1:200

• SKU: ELSE-AB-92644-60
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-E-AB-92644-60
• Green Labware: No
• Package Unit: 60 µl
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine), Rat (Rattus)
• Clonality: Polyclonal
• Application: Immunofluorescence, Western Blotting
• Isotype: IgG
• Host: Rabbit