Description: By immunohistochemistry, this antibody specifically recognizes a protein in melanocytes and melanomas. It reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. This Mab labels formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Conjugate: Purified, BSA-free
Concentration: 1 mg/mL
Storage buffer: PBS, no BSA, no azide
Product Origin: Animal - Mus musculus (mouse)
Clone: NKI-beteb
Entrez Gene ID: 6490
Immunogen: Membranes from a human melanoma metastasis
Expected AB Applications: ELISA (published for clone)/Flow (intracellular) (published for clone)/IHC (frozen) (published for clone)/IF (published for clone)/IP (published for clone)
Verified AB Applications: IHC (FFPE) (verified)
Z-Antibody Applications: Flow, intracellular (published)/IF (published)/IHC, frozen (published)/ELISA (published)/IHC, FFPE (verified)/IP (published)