PP1, CAS 172889-26-8

Src kinase inhibitor

Product Type: Inhibitor

CAS No.: 172889-26-8

MolecularFormula: C16H19N5

Molecular Weight: 281,4

Source: Synthetic

Purity: ≥ 98% (TLC)

Solubility: Soluble in DMSO (25 mg/ml), slightly soluble in 100% ethanol

Appearance: Tan solid

PubChem CID: 1400

Scientific Background: PP1 is a potent and selective Src family protein tyrosine kinase inhibitor. This has a range of effects and implications. Structural studies have revealed that PP1 binds to the ATP-binding site in tyrosine kinases and Ser/Thr kinases. PP1 displays > 8000-fold selectivity over ZAP-70 and JAK2.

References: 1. Hanke J.H., et al. (1996) J. Biol. Chem. 271(2): 695–701.2. Liu Y., et al. (1999). Chem. & Biol. 6(9): 671–678.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-469-5MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-469-5MG
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK