PP2, CAS 172889-27-9

Src kinase inhibitor

Product Type: Inhibitor

CAS No.: 172889-27-9

MolecularFormula: C15H16ClN5

Molecular Weight: 301,8

Source: Synthetic

Purity: >98% (TLC); NMR (Conforms)

Solubility: May be dissolved in DMSO (25mg/mL); or ethanol (3mg/mL, warm)

Appearance: Off-white solid

PubChem CID: 4878

Scientific Background: PP2 is a selective inhibitor of Src-family tyrosine kinases. PP2 has been shown to inhibit Lck, FynT, and phosphorylation of focal adhesion kinase (FAK) and potently inhibits Hck, Lck (p56) and Fyn (p59). PP2 displays > 10000-fold selectivity over ZAP-70 and JAK2.

References: 1. Hanke J.H., et al. (1996) J. Biol. Chem. 271(2): 695–701.2. Liu Y., et al. (1999). Chem. & Biol. 6(9): 671–678.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-470-5MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-470-5MG
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK