Calculated MW: 58
Form: Liquid
Buffer (with preservative): PBS, 0.09% Sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Uniprot ID: P78395
Antigen Species: Human
Immunogen: KLH conjugated synthetic peptide between 476-502 amino acids from the C-terminal region of human PRAME.
Purification: Protein A purified followed by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: preferentially expressed antigen in melanoma
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