Product Description: PRTN3 is a serine protease that broadly targets elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV in vitro, playing a crucial role in extracellular matrix degradation. It modulates endothelial cell barrier function by cleaving and activating the receptor F2RL1/PAR-2 and enhances vascular integrity during neutrophil transendothelial migration. PRTN3 Protein, Human (HEK293, C-His) is the recombinant human-derived PRTN3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PRTN3 Protein, Human (HEK293, C-His) is 224 a.a., with molecular weight of ~34.0 kDa.
Formula: 5657(Gene_ID)P24158 (A26-R249)(Accession)
Molecular Weight: Approximately 34.0 kDa due to the glycosylation.
Compound Purity: 96.00