Formulation: A solid
Formal Name: (2Z)-2-[[3-[(4-chlorophenyl)methoxy]phenyl]methylene]-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazin-3(2H)-one
Purity: ≥95%
Formula Markup: C20H17ClN2O2S
Formula Weight: 384,9
Shelf life (days): 1460
CAS Number: 1627710-30-8
Notes: PSB-CB5 is an antagonist of G protein-coupled receptor GPR18 (IC50 = 0.279 µM).{61849} It is 36-, 36-, and 14-fold selective for GPR18 over GPR55, cannabinoid 1 (CB1), and CB2 receptors, respectively. PSB-CB5 (1 µM) inhibits acrosomal exocytosis induced by the endogenous GPR18 ligand arachidonoyl glycine (NAGly; Item No. 90051) in human spermatozoa.{61850}