PSMA-Val-Cit-PAB-Azide, CAS 2374814-84-1

Product Description: PSMA-Val-Cit-PAB-Azide is a drug-linker conjugate for ADC. PSMA-Val-Cit-PAB-Azide contains the cleavable ADCs linker (Val-Cit-PAB) and a novel small-molecule PSMA-targeted conjugate. It contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups[1].

Applications: Cancer-programmed cell death

Formula: C50H65ClN10O13

References: [1]Aleksei E Machulkin, et al. Synthesis, Characterization, and Preclinical Evaluation of a Small-Molecule Prostate-Specific Membrane Antigen-Targeted Monomethyl Auristatin E Conjugate. J Med Chem. 2021 Dec 9;64(23):17123-17145.

CAS Number: 2374814-84-1

Molecular Weight: 1049.56

Compound Purity: 99.43

Research Area: Cancer

Solubility: DMSO : 200 mg/mL (ultrasonic)

Target: Drug-Linker Conjugates for ADC;PSMA

• SKU: MEXHY-160893-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-160893-5
• Package Unit: 5 mg
• Quantity Unit: STK