PureRec Duplex-Specific Nuclease (DSN)

Description: PureRec Duplex-Specific Nuclease (DSN) is an endonuclease that selectively digests double-stranded DNA (dsDNA) and DNA in DNA-RNA hybrids, exhibiting virtually no activity towards single-stranded DNA (ssDNA) or RNA.
It can discriminate between perfectly matched and non-matched short DNA duplexes. To catalyze cleavage, DSN needs a minimum of 10 bp dsDNA or 15 bp perfectly matched DNA-RNA duplex.
This enzymatic function is reliant upon the presence of Mg2+ ions, with a recommended concentration of 5 mM for most applications.PureRec DSN is overexpressed and extensively purified from a non-animal source and is free of non-specific nucleases or RNases.

• Highest Specificity: Selectively digests dsDNA and DNA in DNA-RNA hybrids; virtually inactive towards ssDNA or RNA.
• Premium Purity: RNase-free, protease-free, and animal-free.
• Thermostable: Able to withstand high temperatures without denaturation or loss in activity.

• SKU: ZYME1020-1000
• Manufacturer: Zymo Research
• Manufacturer SKU: E1020-1000
• Package Unit: 1000 Units
• Quantity Unit: STK