Puromycin HCl, CAS 58-58-2

Translation inhibitor

Product Type: Inhibitor

CAS No.: 58-58-2

MolecularFormula: C22H29N7O5•2HCl

Molecular Weight: 544,43

Source: Synthetic

Purity: >98% (TLC; HPLC); NMR (Conforms)

Solubility: May be dissolved in DMSO (50 mg/ml); or water (50 mg/ml)

Appearance: Off-white powder

PubChem CID: 5891

Scientific Background: Puromycin is an antibiotic that is a protein synthesis inhibitor that causes premature chain termination during translation taking place in the ribosome. Part of the molecule resembles the 3' end of the tRNA. It enters the A site and transfers to the growing chain, causing the premature release. It is not selective for either prokaryotes or eukaryotes.

References: 1.  Azzam and Algranati. (1973) Proc Natl Acad Sci. 70: 3866.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-248-250MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-248-250MG
• Package Unit: 250 mg
• Quantity Unit: STK
• Reactivity: Human