Formulation: A solid
Formal Name: 1,6-dihydroxy-8-methoxy-3-methyl-9,10-anthracenedione
Purity: ≥70%
Formula Markup: C16H12O5
Formula Weight: 284,3
Shelf life (days): 1460
CAS Number: 3774-64-9
Notes: Questin is an anthraquinone that has been found in A. fumigatus and has diverse biological activities.{69775,60294,69776,46738} It inhibits cell division cycle 25B (Cdc25B) phosphatase (IC50 = 34 µg/ml) and reduces the proliferation of SW620 colon cancer cells (GI50 = 0.9 µg/ml).{69775} Questin (50 or 100 µM) reduces the viability of A549 lung cancer cells.{60294} It reduces viral replication in MDCK cells infected with influenza A H1N1 or H3N2 (IC50s = 1.92 and 9.62 µM, respectively).{69776} Questin decreases proliferation of the protozoa T. fetus (MIC = 12.5 µg/ml).{46738}