Target: RAB1A
Conjugate: ATTO 488
Product Type: Monoclonal
Clone Number: 4G10
Immunogen: Full length recombinant Human RAB1A protein
Swiss-Prot: P62820
Purification: Protein G Purified
Storage Buffer: 640.91mM DMSO, 136.36mM Ethanolamine, 9.09mM Sodium Bicarbonate in 90.9% PBS
Concentration: 1mg/ml
Specificity: Detects ~23 kDa. Cross-reacts with RAB1B and RAB1C.
Cellular Localization: Cytoplasm / Endoplasmic reticulum / Endosome / Golgi apparatus / Membrane
Tissue Specificity: Low tissue specificity.
Scientific Background: Rab1A is mostly found in the membrane of the endoplasmic reticulum (ER) and Golgi apparatus and is involved in cell signaling, cancer, and neurodegenerative diseases (1). It regulates protein transport from the ER to the Golgi compartment and is involved in growth hormone secretion (2).
References: 1. Yang, X. et al. (2016) Oncogene. 35(44):5699-57042. pubchem.ncbi.nlm.nih.gov/protein/P62820
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
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