Target: RAB1A.
Conjugate: FITC.
Product Type: Monoclonal.
Clone Number: 7H4.
Immunogen: Full length recombinant RAB1A protein.
Swiss-Prot: P62820.
Purification: Protein G Purified.
Storage Buffer: PBS pH 7.4, 50% glycerol, 0.09% Sodium Azide.
Concentration: 1mg/ml.
Specificity: Detects ~23 kDa. Cross-reacts with RAB1B.
Cellular Localization: Cytoplasm , Endoplasmic reticulum , Endosome , Golgi apparatus , Membrane.
Tissue Specificity: Low tissue specificity.
Scientific Background: Rab1A is mostly found in the membrane of the endoplasmic reticulum (ER) and Golgi apparatus and is involved in cell signaling, cancer, and neurodegenerative diseases (1). It regulates protein transport from the ER to the Golgi compartment and is involved in growth hormone secretion (2).
References: 1. Yang, X. et al. (2016) Oncogene. 35(44):5699-57042. pubchem.ncbi.nlm.nih.gov/protein/P62820.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
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