Stock Concentration: 200 µg/ml
Conjugate Type: Unconjugated
Buffer: Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Shelf Life: 1 year from date of receipt
Protein ID: NP_031576.4
Uniprot ID: O88700
Background: Bloom syndrome protein (BLM) is a RecQ DNA-helicase that plays a role in DNA replication and repair. Mutations and inactivation of BLM result in human syndromes characterized by dwarfism, infertility, erythema, learning disabilities, immune deficiency and predisposition to cancer. BLM has been shown to associate with the BRCA1-associated genome surveillance complex (BASC) which contains BRCA1, MSH2, MSH6, MLH1, ATM, PMS2 and the RAD50-MRE11-NBS1 protein complex.
Immunogen: Between 1366 and C-terminus