Rabbit anti-CD45 Recombinant Monoclonal Antibody (BL-178-12C7)

Stock Concentration: 1000 µg/ml

Conjugate Type: Unconjugated

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free

Shelf Life: 1 year from date of receipt

Protein ID: NP_563578.2

Uniprot ID: P08575

Background: CD45 is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. CD45 acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, CD45 recruits and dephosphorylates SKAP1 and FYN [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P08575].

Immunogen: Between 1256 and C-terminus

• SKU: BEYA700-012CF
• Manufacturer: Bethyl Laboratories
• Manufacturer SKU: A700-012CF
• Package Unit: 100 µl
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: Immunoprecipitation, Western Blotting, Flow Cytometry, Immunohistochemistry, Immunocytochemistry
• Isotype: Whole IgG
• Human Gene ID: 5788
• Host: Rabbit
• Conjugate: Unconjugated