Stock Concentration: 1000 µg/ml
Conjugate Type: Unconjugated
Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
Shelf Life: 1 year from date of receipt
Protein ID: NP_942088.1
Uniprot ID: Q08722
Background: CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. CD47 is a receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q08722].
Immunogen: Residues 19-142 (ECD)