Stock Concentration: 1000 µg/ml
Conjugate Type: Unconjugated
Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Shelf Life: 1 year from date of receipt
Protein ID: NP_005210.3
Uniprot ID: O60610
Background: Diaphanous 1 is a member of the formin family of proteins that is responsible for actin polymerization and nucleation activity and the formation of linear, unbranched actin cables and stress fibers. Diaphanous 1 is a target of the small GTPase, Rho, and couples Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics. Diaphanous 1 has been linked to heritable nonsyndromic progressive hearing loss.
Immunogen: Between 1222 and C-terminus