Rabbit anti-DOG1, clone SP31 (Monoclonal)

Clone Number: SP31

Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers

Concentration: n/a

Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide

Additional info: DOG1 is a calcium-dependent chloride channel protein that is encoded by a gene called TMEM16A (TMEM16 FLJ10261, ANO1, ORAOV2, and AOS2) located on chromosome 11q13. DOG1 has many significant functions such as regulation of the cholinergic activity of gastrointestinal smooth muscle 2 and regulation of both the survival and proliferation of cells. Anti-DOG1 antibody has been shown to be useful in the identification of gastrointestinal stromal tumors (GIST).

References: Kang HG, et al. Mod Pathol. 2011; 24:866-77/Rizzo FM, et al. BMC Cancer. 2016; 16:87/Katoh M, et al.Int J Oncol. 2003; 22:1375-81

• SKU: SANMON3404
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: MON3404
• Package Unit: 1 ml
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunohistochemistry (paraffin)
• Isotype: IgG
• Host: Rabbit
• Conjugate: Unconjugated