Rabbit anti-Human IgG4 Recombinant Monoclonal Antibody (BLR113H)

Stock Concentration: 1000 µg/ml

Conjugate Type: Unconjugated

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free

Shelf Life: 1 year from date of receipt

Uniprot ID: P01861

Background: IgG4 represents only 2-5% of the human IgG subclasses in serum. IgG4 lacks effector functions, such as antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity. IgG4 plays a protective role in allergy by acting as a blocking antibody, and inhibiting mast cell degranulation, but a deleterious role in malignant melanoma, by impeding IgG1-mediated anti-tumor immunity.

Immunogen: Between 75 and 125

• SKU: BEYA700-113CF
• Manufacturer: Bethyl Laboratories
• Manufacturer SKU: A700-113CF
• Package Unit: 100 µl
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: Western Blotting, Immunohistochemistry
• Isotype: Whole IgG
• Human Gene ID: 3503
• Host: Rabbit
• Conjugate: Unconjugated