Background: Phospholipid-mediated signalling on neurons provokes diverse responses such as neurogenesis, pattern formation and neurite remodelling. A recently uncovered novel set of molecules in the mammalian brain, named plasticity-related genes (PRGs) mediate lipid phosphate phosphatase activity and provide evidence for their involvement in mechanisms of neuronal plasticity.
Positive Control: Human brain lysate (Cat. No. X1633C).
Immunogen: Synthetic peptide derived from the LPPRP3 protein.
Purification Method: Antigen Immunoaffiinity Purification.
Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide.
References: [1] The German cDNA Consortium; Blum H., Bauersachs S., Mewes H.W., Weil B., Amid C., Osanger A., Fobo G., Han M., Wiemann S.; Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
[2] Brauer A.U., Savaskan N.E., Kuhn H., Prehn S., Ninnemann O., Nitsch R.; A new phospholipid phosphatase, PRG-1, is involved in axon growth and regenerative sprouting.; Nat. Neurosci. 6:572-578(2003).
UniProt: Q6T4P5.
Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
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