Stock Concentration: 1000 µg/ml
Conjugate Type: Unconjugated
Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
Shelf Life: 1 year from date of receipt
Protein ID: NP_000580.1
Uniprot ID: P05112
Background: IL-4 is a pleiotropic cytokine produced by activated T cells. It acts by binding to the interleukin 4 receptor and STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. IL-4 is considered an important cytokine for tissue repair, counterbalancing the effects of proinflammatory type 1 cytokines, however, it also promotes allergic airway inflammation. Moreover, IL-4, a type 2 cytokine, mediates and regulates a variety of human host responses such as allergic, anti-parasitic, wound healing, and acute inflammation. In an allergic response, IL-4 has an essential role in the production of allergen-specific immunoglobin (Ig) E. [provided by RefSeq, Aug 2020] [taken from NCBI Entrez Gene (Gene ID: 3565)].
Immunogen: Residues 25-153
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