Stock Concentration: 1000 µg/ml
Conjugate Type: Unconjugated
Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Shelf Life: 1 year from date of receipt
Protein ID: NP_055876.2
Uniprot ID: Q9H3R0
Background: JMJD2C is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. JMJD2C, also known as GASC1 (gene amplified in squamous cell carcinoma), has been found to be amplified in several esophageal squamous carcinomas and inhibition of JMJD2C/GASC1 expression results in decreased cellular proliferation.
Immunogen: Between 475 and 525