Rabbit anti-Neurofibromin 1 Recombinant Monoclonal Antibody (BLR345M)

Stock Concentration: 100 µg/ml

Conjugate Type: Unconjugated

Buffer: Phosphate Buffered Saline (PBS) with 0.1% BSA and 0.09% Sodium Azide

Shelf Life: 1 year from date of receipt

Protein ID: NP_001035957.1

Uniprot ID: P21359

Background: Inactivating mutations in NF1 (neurofibromin 1) result in neurofibromatosis type I (NF1) which is characterized by Schwann cell neurofibromas, café-au-lait spots, and benign lesions of the iris. At the cellular level, NF1 functions as a negative regulator of Ras activity. Loss of NF1 leads to increased levels of active Ras-GTP which is important for the formation and maintenance of Schwann cell tumors.

Immunogen: between 2789 and 2839 (C-term)

• SKU: BEYA700-345
• Manufacturer: Bethyl Laboratories
• Manufacturer SKU: A700-345
• Package Unit: 100 µl (50+ tests)
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine)
• Clonality: Recombinant
• Application: Immunoprecipitation, Western Blotting, Flow Cytometry
• Isotype: Whole IgG
• Human Gene ID: 4763
• Host: Rabbit
• Conjugate: Unconjugated