Rabbit anti-OX40/CD134 Recombinant Monoclonal Antibody (BLR042F)

Stock Concentration: 1000 µg/ml

Conjugate Type: Unconjugated

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free

Shelf Life: 1 year from date of receipt

Protein ID: NP_003318.1

Uniprot ID: P43489

Background: OX40/CD134 is a member of the TNF-receptor superfamily that has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested OX40/CD134 plays a role in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [taken from NCBI Entrez Gene (Gene ID: 3659)].

Immunogen: Residues 29-216 (ECD)

• SKU: BEYA700-042CF
• Manufacturer: Bethyl Laboratories
• Manufacturer SKU: A700-042CF
• Package Unit: 100 µl
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: Immunoprecipitation, Western Blotting, Flow Cytometry, Immunohistochemistry, Immunocytochemistry
• Isotype: Whole IgG
• Human Gene ID: 7293
• Host: Rabbit
• Conjugate: Unconjugated