Stock Concentration: 1000 µg/ml
Conjugate Type: Unconjugated
Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Shelf Life: 1 year from date of receipt
Protein ID: NP_078805.3
Uniprot ID: Q6P1J9
Background: Parafibromin, also known as HRPT2 (hyperparathyroidism 2 protein), has been identified as a tumor suppressor that is associated with hyperparathyroidism-jaw tumor syndrome, an autosomal dominant disease characterized by hyperparathyroidism due to parathyroid tumors and ossifying fibromas of the mandible and maxilla. Parafibromin is a component of the PAF1 complex that associates with RNA polymerase II and plays a role in mRNA 3’-end processing and transcription elongation. Parafibromin has been demonstrated to function as an inhibitor of the cell cycle.
Immunogen: Between 250 and 300