Stock Concentration: 1000 µg/ml
Conjugate Type: Unconjugated
Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Shelf Life: 1 year from date of receipt
Protein ID: NP_004567.1
Uniprot ID: Q00005
Background: PP2A is a major serine/threonine phosphatase that is implicated in the negative control of cell cycle progression. It is a trimeric holoenzyme that is comprised of a catalytic, structural, and regulatory subunit. PPP2R2B is a regulatory subunit of PP2A. The regulatory subunits of PP2A are grouped into 3 families: B/PR55, B’/PR61, and B’’/PR72. PPP2R2B encodes a beta isoform of the B/PR55 subunit family. PPP2R2B is brain specific. An expansion of a CAG repeat in the 5’region of PP2R2B is associated with spinocerebellar ataxia type 12 (SCA12), an autosomal dominant neurodegenerative disorder.
Immunogen: Between 50 and 100
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