Stock Concentration: 1000 µg/ml
Conjugate Type: Unconjugated
Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Shelf Life: 1 year from date of receipt
Protein ID: NP_061848.2
Uniprot ID: Q9NYB0
Background: Repressor/activator protein 1 homolog (RAP1) acts both as a regulator of telomere function and as a transcriptional regulator. RAP1 is involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). In contrast to other components of the shelterin complex, RAP1 is dispensible for telomere capping and does not participate in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair. Instead, it is required to negatively regulate telomere recombination and is essential for repressing homology-directed repair (HDR), which can affect telomere length [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NYB0].
Immunogen: Full length protein
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