Clone Number: MRQ-40
Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers
Concentration: n/a
Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Additional info: The antibody reacts with neuroendocrine cells of human adrenal medulla, carotid body, skin, pituitary,thyroid, lung, pancreas, and gastrointestinal mucosa. This antibody identifies normal neuroendocrinecells and neuroendocrine neoplasms. Diffuse, finely granular, cytoplasmic staining is observed, whichprobably correlates with the distribution of the antigen within neurosecretory vesicles. The expressionof synaptophysin is independent of the presence of NSE or other neuroendocrine markers. Antisynaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.
References: Wiedenmann, B, et al. Cell 1985;41:1017-1028/Navone, F et al. J Cell Biol 1986;103:2511-2527/Lyda MH et al. Hum Pathol. 2000 Aug;31(8):980-7
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