Formulation: A solid
Formal Name: (3β)-3-[(O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-β-D-glucopyranosyl-(1→2)-α-L-arabinopyranosyl)oxy]-olean-12-en-28-oic acid
Purity: ≥98%
Formula Markup: C47H76O16
Formula Weight: 897,1
Shelf life (days): 1460
CAS Number: 89412-79-3
Notes: Raddeanin A is a triterpenoid saponin that has been found in A. raddeana and has diverse biological activities.{69696,69697,69698} It binds to amyloid-β (1-42) (Aβ42; Kd = 27.63 µM).{69697} Raddeanin A (4 µM) inhibits the invasion and migration of, and induces apoptosis and cell cycle arrest at the G0/G1 phase in, HeLa cervical cancer cells.{69696} It improves learning and memory in the Morris water maze in mice in the 3xTg model of Alzheimer’s disease when administered at a dose of 10 mg/kg.{69697} Raddeanin A (50 mg/kg) reduces neurological deficits, lesion volume, edema, and microglia lesion infiltration in a mouse model of acute cerebral hemorrhage induced by intracerebral injection of bacterial collagenase VII.{69698}
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